The present work on microwave pyrolysis of bagasse aims at maximizing the bio-oil and gas yield by optimizing reaction time, biomass to microwave absorber ratio, and microwave input power. Further, the performance of two microwave absorbers, glycerol and char, are compared. Experiments are conducted with varying: contact time (5, 10, 20, 30, and 60 min), microwave input power (480, 640, and 800 W), and biomass absorber ratios (1: 0.25, 1: 0.5, and 1: 0.75). The maximum bio-oil and gas yield is obtained at reaction time of 30 min, biomass absorber ratio of 1: 0.75, and microwave power of 800 W.