In this article, the anaerobic digestion of food waste was studied on a laboratory scale continuously stirred tank reactor, operating at 37 degrees C under quasi-continuous conditions. The change of organic loading rate led to performance failure in the reactor. The aim of this work is to determine a reliable parameter, which could be used as an indicator of process imbalance during anaerobic digestion of food waste in the continuously stirred tank reactor anaerobic reactor. The results showed that intermediate alkalinity/partial alkalinity ratio can predicate the failure in the food waste anaerobic digestion.