Heat capacity of methyl alpha-n-glucopyranoside (a-MeG) was measured by differential scanning calorimetry at the temperatures ranging from 298.15 to 513.15 K. Melting point, enthalpy and entropy of fusion, enthalpy HT-11298.15 IC, and entropy ST-S29815 K were determined. Thermal decomposition of alpha-MeG was investigated using thermogravimetric analysis under pure nitrogen atmosphere. Ozawa-Flynn-Wall and ASTM models were used to calculate the activation energy and pre-exponential factor. Solubilities of aMeG in methanol were measured within the temperature range of 293.15-318.15 K by using a synthetic method under atmospheric pressure. The modified Apelblat, Ah, Wilson and NRTL models were applied to correlate the experimental data. The calculated results show good agreement with the experimental data and Wilson model is slightly more accurate than modified Apelblat, Ah and NRTL models. The dissolution enthalpy, entropy, and Gibbs free energy were calculated by the Van't Hoff equation. The excess enthalpy of the solution can be evaluated by the model. (C) 2015 Elsevier B.V. All rights reserved.