Autoignition properties of diethoxymethane/O-2/Ar mixtures were systematically investigated using a shock-tube facility under various ignition conditions, including reflected shock pressures of 2-10 x 10(5) Pa, temperatures of 1065-1370 K, and equivalence ratios of 0.5, 1.0 and 2.0. Ignition delay times were determined by measuring the time interval between electronically excited CH/emission and reflected shock pressure signals monitored at shock-tube sidewall. An empirical correlation for ignition delay times as a function of temperature, pressure and equivalence ratio was deduced by linear regression analysis. A chemical kinetic mechanism describing the high-temperature oxidation of diethoxymethane was proposed. The theoretical predictions match experimental results quite well. Sensitivity and reaction pathway analyses were employed to identify dominant reactions and fuel consumption paths during the ignition process. To our knowledge, we are the first one to present the ignition delay time measurements of gas-phase diethoxymethane. (C) 2015 Elsevier Ltd. All rights reserved.