In this paper, a numerical study has been carried out to investigate the steady-state mixed convection around two heated horizontal cylinders in a square two-dimensional enclosure. The cylinders are located at the middle of the enclosure height and the walls of the cavity are adiabatic. Streamlines and isotherms are produced and the effects of cylinder diameter, Reynolds number, and Richardson number on the heat transfer characteristics are numerically analyzed. The average Nusselt number over the surface of cylinders and average nondimensional temperature in the enclosure are also presented. The results show that both heat transfer rates from the heated cylinders and the dimensionless fluid temperature in the enclosure increase with increasing Richardson number and cylinder diameter. However, the trend of average Nusselt number and nondimensional temperature variation is completely opposite when Reynolds number increases. In addition, by increasing the cylinders diameter and Richardson number, the left cylinder is less affected by the inlet flow than right one.