This paper presented an experimental investigation on the pressure drop during flow boiling of liquefied natural gas in a vertical micro-fin tube. The effect of heat flux, mass flux and inlet pressure on the frictional pressure drop during two-phase flow of liquefied natural gas was analyzed. Results showed that the two-phase flow pressure drop increased with the increasing of heat flux and mass flux but decreased with the increasing of inlet pressure. The calculated results with Miyara correlation, Oliver correlation, Hu correlation and Goto correlation showed that the Hu correlation could give the best prediction which also has a big error. Thence a new correlation was developed based on the experimental data. (C) 2015 Elsevier Ltd. All rights reserved.