Data on corresponding solid liquid equilibrium of Gibberellin A(4) (GA(4)) in different solvents is essential for a preliminary study of industrial applications. In this paper, the solid liquid equilibrium of GA(4) in Water, methanol, ethanol, isopropanol, 1-butanol, acetonitrile,, acetone, and ethyl acetate was explored in the temperatures (from 278.15 K to 333.15 K) under atmosphere pressure. For the temperature range investigated, the solubility of GA(4) in the solvents increased with increasing temperature. From 278.15 K to 333.15 K, the solubility of GA(4) in isoptopanol is superior to other selected solvents. The modified Apelblat model, the Buchowski-Ksiazaczak lambda h model, and the ideal model were adopted to describe and predict the change tendency of solubility. Computational results showed that the modified Apelblat model has advantages than the other two models. In addition, the calculated thermodynamic parameters indicated that in each studied solvent the dissolution of GA(4) is endothermic, nonspontaneous, and an entropy-driven process.