The ability of (L)-tyrosine molecules to act as a template and to facilitate the nucleation of unstable beta polymorph in the solution has been revealed through in-situ nucleation study. This nucleation of beta occurs along with the existing a nucleation at the critical concentration of additive in the solution. The presence of (L)-tyrosine molecules lowers the inherent barrier that exists for beta nucleation in the solution. No nucleation of gamma was observed over the entire range of concentrations studied. The molecular recognition capability and stereo selective inhibitory action of the added (L)-tyrosine molecules towards glycine molecule have been successfully revealed in terms of habit modification observed in the nucleated polymorphs. In the case of a polymorph, (L)-tyrosine induces a change in the morphology along the enantiopolar -b direction while in the case of beta polymorph, habit modification from needle to plate like structure is observed. With the increase in time span, solution mediated phase transformation from beta to a polymorph has been observed in the solution. Analytically the nucleation parameters of a and beta polymorphs were estimated based on Classical Nucleation Theory. Form of crystallization of the nucleated polymorphs of glycine was confirmed by a powder x-ray diffraction analysis. (C) 2015 Elsevier B.V. All rights reserved.