We report the production of a novel nanoflower material of Mn-3(PO4)(2)@BSA hybrid which is made of both protein and manganese (II) phosphate, and its application as a new support material for platinum nanoparticles (PtNPs). The Mn-3(PO4)(2)@BSA@PtNPs catalyst is synthesized using this new material. The average size of PtNPs on the Mn-3(PO4)(2)@BSA nanoflower is approximately 2 nm. The obtained Mn-3(PO4)(2)@BSA@PtNP5 nanocomposites are characterized by X-ray diffraction, high resolution transmission electron microscopy, and scanning electron microscopy. Electrochemical results show that the Mn-3(PO4)(2)@BSA@PtNP5 catalyst also shows excellent electrocatalytic activity toward methanol oxidation with higher electrochemically active surface area. The microstructure of the supporting material serves a crucial function in the electrochemical performance of the Pt-based catalyst. (C) 2015 Elsevier B.V. All rights reserved.