화학공학소재연구정보센터
Journal of the American Ceramic Society, Vol.98, No.3, 694-697, 2015
Chelate Bonding Mechanism in a Novel Magnesium Phosphate Bone Cement
A novel approach to harden magnesium phosphate cements was tested using phytic acid (C6H18O24P6) solutions as chelation agent. In addition to complex formation, a cementitious dissolution and precipitation reaction led to the formation of newberyite (MgHPO(4)3H(2)O) as the hydrated form of the farringtonite [Mg-3(PO4)(2)] raw powder. The set cements showed good mechanical properties (up to 65MPa in compression) displaying a doubling of the compressive strength of conventional newberyite forming cements despite of a significantly lower degree of cement conversion. An increasing phytic acid concentration from 10% to 30% had a retarding effect on the setting time (11-16min), decreased the pH close to acidic conditions (pH=5-4) and increased the maximum setting temperature (26 degrees C-31 degrees C), but none of these factors reached critical values. The presented strategy was successful in fabricating a good workable, novel mineral biocement with promising characteristics for biomedical applications.