In situ measurements using simultaneously Raman spectroscopy and high energy wide angles X-rays scattering (HE-WAXS) were carried out during uniaxial tensile tests of different polypropylene blends (neat isotactic polypropylene - iPP, high impact polypropylene - iPP/EPR, and high impact polypropylene filled by 7% wt of m-talc particles - iPP/EPR + mu-talc) at various strain rates (5.10(-3) s(-1), 10(-3) s(-1) and 5.10(-4) s(-1)). Tensile tests were performed using the VideoTraction (TM) system to determine the true mechanical behavior of materials in a Representative Volume Element (RVE) where microstructural analyses by the both experimental techniques are obtained. Evolutions of the macromolecular chains orientation have been obtained live at the macromolecular and crystalline cell scales. Experimental results show both that over the course of adding charges in the iPP matrix or increasing the true strain rate, this major micromechanism of deformation of semi-crystalline polymers would be less and less important until its complete disappearance in case of iPP/EPR filled by m-talc particles. Moreover, correlations made between both techniques evidence similar results over a wide range of true strains. However, measurements diverge at lower and higher strains due to singularities of each both techniques which are discussed in terms of experimental protocols and materials microstructure modifications (transient mesophase, volume damage). Finally, the determination of the true intrinsic mechanical behaviors show similar stress hardening slopes for the three studied iPP blends which means that they all present an highly fibrillar microstructure. The differences of macromolecular chains orientation levels between each material is then discussed in terms of analysis volume of both techniques which could be responsible of their lack of accuracy in case of filled polymers. (C) 2015 Elsevier Ltd. All rights reserved.