A developed method based upon impregnation of Isonitroso-4-methyl-2-pentanone (HIMP) as extractant on Amberlite XAD-4 for Th4+ enrichment and spectrophotometric determination in a variety of samples were reported. This Extractant Impregnated Resin (EIR) sorbent is characterized by Fourier Transforms-Infrared Spectrometer (FT-IR), Field Emission-Scanning Electron Microscope (FE-SEM), and Brunauer-Emmett-Teller (BET) analysis. The EIR packed in column was studied for various parameters to optimize sorption desorption condition for Th4+. Sorption of Th4+ from aqueous solution onto EIR was studied and equilibrium isotherms, kinetics were determined. These investigations facilitate its determination in different real samples. The developed method was validated by analyzing lake sediment standard reference material (IAEA-SL-1).