The Defense Waste Processing Facility (DWPF), responsible for vitrifying high-level waste (HLW) at the Savannah River Site (SRS), is planning to introduce glycolic acid as a reductant during chemical conditioning of the waste prior to vitrification. A portion of this glycolic acid may be recycled back to the tank farm as sodium glycolate. Since glycolate can serve as a complexing agent for a variety of metallic ions, recent studies were performed to examine the effect of glycolate on the removal of Sr and actinides by monosodium titanate (MST) and modified MST (mMST) and the separation of Cs by the caustic-side solvent extraction (CSSX) process.