Based on a modified version of standard chips for fast differential scanning calorimetry, DSC of liquid samples has been performed at temperature scan rates of up to 1000 degrees C/s. This paper describes experimental results with the protein lysozyme, bovine serum, and olive oil. The heating and cooling rate of the sensor is measured for temperature scan rates of up to 1300 degrees C/s with water and 2-butanol, in the temperature range of-90 degrees C/s to +130 degrees C/s. The lysozyme is measured at temperature scan rates varying from 10 degrees C/s to 400 degrees C/s and in concentrations between 0.1% and 10% protein by weight. The bovine serum measurements show two main peaks, in good agreement with standard DSC measurements. Olive oil has been measured, with good agreement for the cooling curve and qualitative agreement for the heater curve, compared to DSC measurements. (C) 2014 Elsevier B.V. All rights reserved.