We model the nucleation and dynamical behavior of defects from an inhomogeneous surface configuration using fast Q-tensor method. A fast Q-tensor method, which can model the defect dynamics in a liquid crystal director field, is applied to model the defect nucleation and dynamics. From the numerical modeling, we confirmed that surface inhomogeneity which makes strong strain energy in the local liquid crystal director field could cause defects. Experimental result has compared with numerical modeling in order to verify the simulation of the defect nucleation.