Photonic crystals having a three dimensional periodic structure have attracted much attention from both fundamental and practical points of view, because of their unique properties in controlling the propagation of light. One of the promising techniques for fabricating three-dimensional (3D) photonic crystal is the preparation of self-assembled colloidal crystal. In this study, we synthesized monodisperse polymer spheres having photo-cross-linking groups which were synthesized by co-polymerization of styrene and vinyl cinnamate. Then we prepared colloid crystal from photo-cross linking beads, investigated about application for microfabrication of colloidal crystal from the change of solubility from cross linking by UV light.