Pulsed-laser induced fragmentation and dissociation of DNA immobilized on gold nanoparticles

Niidome Y; Niidome T; Yamada S; Horiguchi Y; Takahashi H; Nakashima K

Molecular Crystals and Liquid Crystals, Vol.445, 201-206, 2006

DOI10.1080/154214005003672124 Export Citation

Pulsed-laser induced fragmentation and dissociation of DNA immobilized on gold nanoparticles

Niidome Y, Niidome T, Yamada S, Horiguchi Y, Takahashi H, Nakashima K

Plasmid DNA was immobilized on positively-charged gold nanoparticles (GNPs). Pulsed-laser irradiation induced fragmentation and dissociation of DNA from the GNP-DNA complexes. Dissociation of DNA without degradation was achieved when 80- mJ/pulse of laser light irradiated the GNP-DNA complexes.

Keywords:controlled release;gold nanorod;plasmid DNA