Among the different biofluids in the human body, albumin is the most important plasma proteins circulating in the bloodstream and our paper are focused on the behavior of pure titanium in albumin solution. The samples investigated were immersed for 10 days in a mixture of human body plasma and bovine serum albumin solution with concentrations of 2% and 10% in weight. The analysis by diffuse reflectance in the 220-2300 nm domain, and in the mid-infrared range (400-4000 cm(-1)) was performed. The albumin adsorption at interface was put in evidence from spectral data and is found to be most important in the sample containing a higher concentration of albumin, regarding the relative band intensity. This is in agreement with the electrochemical results showing a better stability at a smaller albumin concentration according to a higher corrosion rate.