High-resolution annular dark-field scanning transmission electron microscopy (ADF-STEM) imaging was applied for structural observations of organic crystals so as to achieve quantitative atomically resolved images. In particular, a low angle annular dark-field method (LAADF-STEM) was found to be highly advantageous for radiation sensitive organic materials, because stronger thermal diffuse scatterings can be utilized for imaging. So called quantitative Z-contrast images of organic molecules at atomic resolution were demonstrated in several organic crystals.