The effect of texturing interfaces on the optical and photoelectric properties of anisotype and isotype organic (OS)/inorganic (IS) semiconductor heterojunctions has been investigated. p-(Pentacene) and n-(methyl perylene pigment, MPP) type organic semiconductor layers were evaporated on n-GaAs and p-InP substrates, respectively, with flat substrates and the substrates textured by chemical anisotropicetching (with a microrelief of the quasigrating type). The spectra of the light reflectance and the short-circuit photocurrent for the Au/OS/IS heterostructure were measured and analyzed to distinguish the contribution of the photocurrent generated in the OS layer. A considerable enhancement of the photocurrent generated in both. inorganic and organic semiconductors was found for structures with textured interface.