In this study, tetrafluoro-tetracyano-quinodimethane (F-4-TCNQ)-doped poly(3,4-ethylenedioxythiophene): poly(styrene sulfonate) (PEDOT:PSS) was spin-coated on a pre-patterned ITO glass and used as hole conducting layer materials in organic photovoltaic cells. The multi-layered ITO/F-4-TCNQ-PEDOT:PSS/CuPc/CuPc: C60/C60/BCP/Al organic photovoltaic cells were fabricated to evaluate the J - V characteristics such as short circuit current (J(sc)), open circuit voltage (V-oc), fill factor (FF) and energy conversion efficiency (eta(e)) of the device. A higher power conversion efficiency obtained from the device with a concentration of 0.1 wt% F-4-TCNQ in the PEDOT:PSS layer was achieved compared to those adopted from device without F-4-TCNQ doping in the PEDOT:PSS layer, and current density-voltage characteristics was also improved well with incorporation of F-4-TCNQ in PEDOT:PSS films.