Two Zn(II)-containing complexes based on fluconazole, {[Zn(HFlu)(2)(IPA)]center dot 9H(2)O}(n) (1), {[Zn(HFlu)(2)(OH-BDC)]center dot 8H(2)O}(n) (2) (HFlu = fluconazole; 2-(2,4-difluoro- phenyl)-1,3-bis(1,2,4-triazol-1-yl)-propan-2-ol; H(2)IPA = isophthalic acid; OH-H2BDC = 5-hydroxyisophthalic acid) have been synthesized and structurally characterized. Complex 1 and 2 are both a one-dimensional (1D) tubular structure with the distorted dinuclear zinc rectangular-shaped cavity, and large free water molecules involved in strong O-H center dot center dot center dot O and O-H center dot center dot center dot N hydrogen bonds are accommodated in the 1D tubular structure. The thermal stabilities and photoluminescent properties of the coordination polymers have also been investigated.