From the aerial parts of Geranium pyrenaicum Burm., a new flavonol glycoside, kaempferol 3-O-(2",3"-di-O-galloyl)-beta-D-glucopyranoside (7), along with 6 known related glycosides [kaempferol 3-O-beta-D-glucopyranoside (1), quercetin 3-O-beta-D-glucopyranoside (2), quercetin 3-O-beta-D-galactopyranoside (3), kaempferol 3-O-(2"-O-galloyl)-beta-D-glucopyranoside (4), quercetin 3-O-(2"-O-galloyl)-beta-D-glucopyranoside (5) and quercetin 3-O-(2",3"-di-O-galloyl)-beta-D-glucopyranoside (6)] and the ellagitannins corilagin (8) and tellimagrandin I (9) were isolated. Their structures were established from spectroscopic studies (UV, FAB-MS, H-1 and C-13-NMR, H-1-H-1 COSY, HETCOR, HMBC). Compounds 1-7 were evaluated for antileishmanial activity against a panel of Leishmania species (L. major, L. donovani and L. amazonensis), indicating appreciable in vitro activities (IC50 4-27 nM) when compared with Pentostam (IC50 10-11 nM).