Turkish Journal of Chemistry, Vol.35, No.3, 361-374, 2011
Tridentate ligands derived from L-tert-Leucine for the Cu(II) mediated asymmetric Henry reaction
Chiral tridentate Schiff base ligands were prepared from L-tert-Leucine and used as catalysts in the asymmetric Henry reaction in the presence of Cu(II) ions. Moderate enantiomeric excesses (up to 66%) and yields (up to 76%) of the desired beta-nitroalcohols were obtained.
Keywords:Asymmetric Henry reaction;chiral Schiff base;L-tert-Leucine;amino alcohol;tridentate ligand