Process Biochemistry, Vol.38, No.6, 877-880, 2003
Determination of significant parameters for improved griseofulvin production in a batch bioreactor by Taguchi's method
Taguchi's method was applied to evaluate the significant parameters for griseofulvin production by Penicillium griseofulvum MTCC 1898 in a batch bioreactor. Physical parameter, viz., controlled pH, agitation and aeration had a significant influence on griseofulvin production when compared with chemical parameters and were considered as significant ones. (C) 2002 Published by Elsevier Science Ltd.