The performance of a hybrid solid acid catalyst consisting of a physical mixture of -Al2O3 and H-ZSM-5 in terms of the rate and heat duty for solvent regeneration (i.e., CO2 stripping) of a CO2-rich MEA solution was compared with the individual performance of -Al2O3, H-ZSM-5, and H-Y solid acid catalysts using MEA (2-7 mol/L), with initial CO2 loading of 0.5 mol CO2/mol MEA at 378 K. It was observed that any catalyst significantly decreased the energy required for CO2 regeneration. The performance of the catalysts investigated ranked as follows: -Al2O3/H-ZSM-5=2/1>-Al2O3>H-ZSM-5>H-Y if the process is in the lean CO2 loading region whereas it was H-ZSM-5>-Al2O3/H-ZSM-5=2/1>-Al2O3>H-Y if the process is in the rich CO2 loading region. These results highlight the joint dependence on BrOnsted/Lewis acidity and mesopore surface area of heat duty for solvent regeneration. (c) 2015 American Institute of Chemical Engineers AIChE J, 62: 753-765, 2016