Chemistry Letters, Vol.44, No.3, 378-380, 2015
DNA Binding of Pentaamino[60]fullerene Synthesized Using Click Chemistry
We have synthesized pentaaminofullerene 4 by the introduction of dimethylamino groups using a click reaction. The dendritic fullerene amphiphile showed a low critical micelle concentration of 3.6 +/- 0.5 mu M. 4 is shown to be an efficient DNA binder that compacts DNA into nanoparticles at low nitrogen/phosphorus ratios.