Refurbishment, as part of the construction industry, has a strong global impact, not only from the viewpoint of economies but also from social and energy-efficiency perspectives. A thermal refurbishment process, in particular, involves numerous decisions and choices; the decision-makers being ultimately confronted with two major questions: which criterion should be adopted in the choice of the refurbishment construction solutions and which refurbishment construction solutions should be chosen? In this paper, a criterion based on technical and economic points of view is proposed, aiming to identify the cost-optimal package of energy efficient solutions from among a set of possible refurbishment measures, within the life cycle of buildings. Sensitivity analyses are also performed so that the results may help the decision-maker choose the appropriate refurbishment solutions to be adopted when different discount rates and building orientations are taken into consideration. A total of seven scenarios, for a macroeconomic perspective, and nine, for a financial perspective, are performed. The costoptimal methodology adopted, following the Directive 2010/31/EU (2010) recommendations, is applied to a Portuguese reference building. The analysis carried out allows obtaining low global life cycle costs solutions and points towards nearly Zero Energy Building (nZEB) concept. The results are important for drawing national political instruments on buildings energy efficiency. (C) 2016 Elsevier Ltd. All rights reserved.