A novel electrochemical sensor based on the silver decorated carbon nanotube is reported here for the accurate and rapid determination of hydrogen peroxide. The hybrid nanostructure was synthesized separately and characterized by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX) and X-ray photoelectron spectroscopy (XPS). The high focus on the silver-based hydrogen peroxide sensor spurred us to investigate the determination of the electrocatalytic activity towards hydrogen peroxide. The as-prepared electrochemical senor exhibited well-defined response to the reduction of hydrogen peroxide. The detection limit of hydrogen peroxide was found to be 1.6 mu M, which was lower than the certain enzyme-based biosensor. (C) 2011 Elsevier B.V. All rights reserved.