The dilution enthalpies of four derivatives of monosaccharides, namely 2-deoxy-D-glucose (2-DGlu), N-acetyl-D-glucosamine (GluNAc), 2-deoxy-D-galactose (2-DGal) and N-acetyl-D-galactosamine (GalNAc), in aqueous NaCl solutions of various molalities (b = 0-3.0 mol . kg (1)) have been determined respectively at T = 298.15 K by isothermal titration calorimetry (MicroCal ITC200). The corresponding values of enthalpic pairwise self-interaction coefficients (h(2)) have been calculated according to the McMillan-Mayer theory. It was found that across the range studied of ionic strength (I) or molality (b = I), the h(2) coefficients are all positive, in the order h(2) (GluNAc) > h(2) (GalNAc) > h(2) (2-DGlu) > h(2) (2-DGal), and decrease gradually after increasing first up to a maximum at b approximate to 1.5 mol . kg (1). The effects of ionic strength (I) on the trends of h(2) have been discussed from the point of view of complex (solute + solute) and (solute + solvent) interactions in solutions. (C) 2015 Elsevier Ltd. All rights reserved.