In this paper we present experimental data on heat transfer and pressure drop characteristics at flow boiling of refrigerant R-134a in a horizontal microchannel heat sink. The primary objective of this study was to experimentally establish how the local heat transfer coefficient and pressure drop correlate with the heat flux, mass flux, and vapor quality. The copper microchannel heat sink contains 21 microchannels with 335 x 930m(2) cross section. The microchannel plate and heating block were divided by the partition wall for the local heat flux measurements. Distribution of local heat transfer coefficients along the length and width of the microchannel plate was measured in the range of external heat fluxes from 50 to 500 kW/m(2); the mass flux varied within 200-600kg/m(2)-s, and pressure varied within 6-16 bar. The obvious impact of heat flux on the magnitude of heat transfer coefficient was observed. It showed that nucleate boiling is the dominant mechanism for heat transfer. A new model of flow boiling heat transfer, considering nucleate boiling suppression and liquid film evaporation, was proposed and verified experimentally in this paper.