Upgrading pyrolysis oil by hydrodeoxygenation (HDO) is a promising route for the production of advanced biofuels. The proper reaction conditions and catalysts are important for the success of this process. Previously our research group investigated the ratio of Zn and Pd on the synergistic effect for HDO bio-oil upgrading. This present research focuses on determining the optimal reaction conditions for HDO conversion of pyrolysis oil produced from pine sawdust. Temperatures of 150, 200 and 250 degrees C and hydrogen pressures of 1.38, 2.76 and 4.14 MPa were evaluated. Syngas, liquids and coke were the primary products evaluated. Syngas was characterized using a Gas chromatography (GC). The liquids were characterized using a Gas chromatography-mass spectrometry (GC-MS). Increasing reaction temperature resulted in increased coke yields. Treatment at 250 degrees C and 1.38 MPa resulted in the highest hydrocarbon content (6.06%). The treatment at 200 degrees C and 1.38 MPa produced the largest amounts of hydrocarbons in C-6-C-12 range (5.07%). The physicochemical characterizations further support the GCMS results. Syngas analysis revealed that higher hydrogen pressure leads to increased hydrogen consumption and results in more oxy-compounds conversion to hydrocarbons. The syngas analysis also supports the liquid analysis result. (C) 2016 Elsevier Ltd. All rights reserved.