Self-supported two-dimensional metal oxide nanosheet arrays have attracted great attention in lithium-ion batteries (LIBs) due to their superior structure advantages such as large surface area, good structure stability, and high electronic conductivity compared to one dimensional (1D) nanowires. Herein, we design the self-supported mesoporous CoFe2O4/CoO nanosheet arrays assembled from the nanowires precursor based on the combination of hydrothermal and atomic layer deposition techniques. The assembled CoFe2O4/CoO nanosheets exhibit an ultra-high initial charge capacity of 1705 mAhg(-1) and good cycling stability (1043 mAhg(-1) after 50 cycles) when directly used as a binder-free anode of LIBs.