A rapid access to 2,2'-bithiazole-based copolymers has been developed on the basis of the sequential palladium-catalyzed C-H/C-X and C-H/C- H coupling reactions. To assemble a "copolymer" through homopolymerization, a type of symmetric A-B-A-type building block is designed as the monomer and prepared via the regioselective C5-H arylation of thiazole. A PdCl2/CuCl-cocatalyzed oxidative C-H/C-H homopolymerization has been established to afford the 2,2'-bithiazole-based copolymers with high M-n (up to 69400). The current protocol features atom-and step-economy and exhibits a potential in the highly efficient construction of conjugated copolymers.