An eco-friendly procedure for the efficient synthesis of diethyl α-aminophosphonates in aqueous media using natural acids as a catalyst

Abdelkader Hellal; Salah Chafaa; Lasnouni Touafri

Korean Journal of Chemical Engineering, Vol.33, No.8, 2366-2373, August, 2016

DOI10.1007/s11814-016-0098-2 Export Citation

An eco-friendly procedure for the efficient synthesis of diethyl α-aminophosphonates in aqueous media using natural acids as a catalyst

Abdelkader Hellal^{1, 2, †}, Salah Chafaa², and Lasnouni Touafri³

¹Laboratoire d’Electrochimie des Matériaux Moléculaires et des Complexes (LEMMC), Département Génie des Procédés, Facult de Technologie, Universit Ferhat Abbsas Sétif-1, Algeria
²Laboratoire de Valorisation des Substances Naturelles(LVSN), Universit Djilali Bounaâma de Khemis Miliana, 44225, Algeria
³Laboratoire de Physique et Chimie des Matériaux(LPCM), Universit Mouloud MAMMERI de Tizi-Ouzou, 15000, Algeria

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WE describe a new, convenient and high yielding procedure for the preparation of diethyl α-aminophosphonates in water by one-pot reaction of aromatic aldehydes, aminophenols and dialkyl phosphites in the presence of a low catalytic amount (10mol%) of citric, malic, tartaric, and oxalic acids as a naturel, recyclable and highly stable catalyst.

Keywords:α-Aminophosphonates;Aminophenols;Natural Acids;Aqueous Media;Kabachnik-Fields Reaction