The properties of ZnO nanorods (ZnONRs) decorated with platinum nanodendrites (PtNDs) were studied. Various sizes of PtNDs were synthesized and spin coated onto ZnONRs, which were grown on indium-titanium-oxide (ITO) substrates through a low-temperature hydrothermal method. Scanning electron microscopy and X-ray diffraction analyses were conducted to analyze the morphology and structural properties of the electrodes. The effects of PtND size, glucose concentration, and Nafion amount on glucose-sensing properties were investigated. The glucose-sensing properties of electrodes with immobilized glucose oxidase (GO) were measured using cyclic voltammetry. The bio-electrochemical properties of Nafion/GO(x)/42 nm PtNDs/ZnONRs/ITO glucose sensor was observed with linear range within 1-18 mM, with a sensitivity value of 5.85 A/mM and a limit of detection of 1.56 mM. The results of this study indicate that PtNDs/ZnONRs/ITO has potential in glucose sensor applications. (C) 2016 Elsevier B.V. All rights reserved.