A typical biogas system with three utilization pathways, i. e., biogas upgrading, biogas combined heat and power (CHP), biogas solid oxide fuel cells (SOFCs) were designed. It was assessed from the viewpoint of energy, environment and economy by using energy efficiency, green degree and net present value index respectively. The assessment considered the trade-off relationships among these indexes, which is more comprehensive than previous systematic evaluation work only included single or two of the pathway(s) by using one or two of the index(es). Assessment results indicated that biogas upgrading pathway has the highest systematic energy efficiency (46.5%) and shortest payback period (8.9 year) with the green degree production is the lowest (9.29 gd/day). While for biogas SOFC pathway, although the green degree production is the highest (21.77 gd/day), the payback period is longer (14.5 year) and the energy efficiency is 13.6% lower than the biogas upgrading pathway. (C) 2016 Elsevier Ltd. All rights reserved.