Enhancement of the oxygen reduction reaction (ORR) was examined with Pd3Pb ordered intermetallic nanoparticles (NPs) supported on titania (Pd3Pb/TiO2). The Pd3Pb/TiO2 catalyst was synthesized by a conventional wet chemical method with Pd and Pb ion precursors, a reducing agent and TiO2 powder under ambient temperature. X-ray diffraction, transmission electron microscopy, and X-ray photoelectron spectroscopy measurements indicated the formation of the ordered intermetallic phase of Pd3Pb in the NP form on the TiO2 surface. Electrochemical measurements showed that the Pd3Pb/TiO2 catalyst markedly enhanced the ORR in an alkaline environment due to the unique surface of Pd3Pb NPs and the strong interaction between Pd3Pb and TiO2 compared with TiO2-supported Pd, Pt, and PtPb NPs. The onset potential of Pd3Pb/TiO2 was shifted toward a higher potential by 110-150 mV compared with Pd/TiO2, PtPb/TiO2, and Pt/TiO2. [GRAPHICS] .