Ternary oxide nanocrystals (TONs) have received growing attention for their great potential applications in optoelectronics and electrochemistry despite the current scarcity of universal, facile, and green synthesis methods. Here, we introduce a universal laser-hydrothermal approach for various TONs and demonstrate their potential for high-performance photodetectors (PDs) and pseudocapacitors. The obtained clean surface is derived by laser ablation in liquid (LAL) and subsequent hydrothermal growth. The LAL-generated precursors contain many kinds of highly reactive species, including H+, OH-, metal ions, and clusters, which facilitate the fast and facile formation of various TONs in the subsequent hydrothermal process. The universality of the method is systematically proven by the synthesis of a series of TONs, including Zn2GeO4, NiCo2O4, Zn2SnO4, ZnFe2O4, ZnMnO3, and Fe2GeO4. Significantly, the absence of chemical additives, such as surfactants, guarantees highly clean surfaces, which further benefits the electron transport through the nanocrystals, and thus in the resultant devices. This is also exemplified by a Zn2GeO4-nanorod-based, deep-ultraviolet PD and NiCo2O4 nanocrystal supercapacitors.