In this study, the influence of disperser induced microwave pretreatment was investigated to analyze the proficiency of floc disruption on subsequent disintegration and biodegradability process. Initially, the flocs in the sludge was disrupted through disperser at a specific energy input of 25.3 kJ/kg TS. The upshot of the microwave disintegration presents that the solids reduction and solubilization of floc disrupted (disperser induced microwave pretreated) sludge was found to be 17.33% and 22% relatively greater than that achieved in microwave pretreated (9.3% and 16%) sludge alone. The biodegradability analysis, affords an evaluation of parameter confidence and correlation determination. The eventual biodegradability of microwave pretreated, and floc disrupted sludges were computed to be 0.15 (g COD/g COD) and 0.28 (g COD/g COD), respectively. An economic assessment of this study offers a positive net profit of about 104.8 USD/ton of sludge in floc disrupted sample. (C) 2016 Elsevier Ltd. All rights reserved.