In this report, superhydrophobic titanium-based materials were synthesized using the combination of sandblasting and alkali-etching to construct topology, and the self-assembly fluorination process with fluorocarbon coating. The as-prepared superhydrophobic titanium-based materials possessed an echinus-like topology, and obtained an efficient drag-reduction property, showing maximum decline value of 26% in glycerin water solution. Additionally, due to the introduction of a titanate coupling agent, the as-prepared titanium-based materials can maintain the superhydrophobicity for 8 months in the seawater, indicating good durability.