Prediction of gasifier performance is generally carried out using two techniques, namely, kinetic modeling and chemical equilibrium modeling. The later model was adopted in the current study because it is not governed by any of the gasifier design parameters. Chemical equilibrium modeling was deployed to compute and ascertain the influence of the equivalence ratio (ER), moisture content (MC), and reaction temperature (RT) on corn cob gasification. The simulation studies reveal that, for a gasification system, with an increase in the ER (for a constant MC and RT), the higher heating value (HHV) of producer gas drops, with an increase in the MC (for a constant ER and RT), the H-2 content increases but CO decreases, and with an increase in the RT (for a constant ER and MC), both the H-2, and CO contents increase. An attempt was made toward validating the simulated results by subjecting corn cob to gasification in a 25 kW(th) downdraft gasifier. A comparative analysis on the simulation results and experimental outcome revealed that the mole fraction of H-2, CO, CO2, and CH4 predicted by the model was inferred to deviate from the experimental results by +36.62, -26.56, -13.08, and -22.31%, respectively. The HHV of the gas predicted by the model was observed to deviate from the experimental outcome by +27.51%. These deviations could be attributed to certain non-trivial assumptions made in simulation studies. However, at an ER greater than 0.3, the composition of gas and HHV predicted by the model and experimental values concur well.