Macromolecular Research, Vol.24, No.10, 887-891, October, 2016
Diverse Morphologies of Self-Aggregates from Dodecyl Chain Grafted Poly(2-Hydroxyethyl Aspartamide) in Aqueous Solution
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A series of amphiphilic graft copolymers, poly(2-hydroxyethyl aspartamide) grafted with dodecyl chains with different degree of substitution (DS), were synthesized and their self-aggregates showing various morphologies in aqueous media were prepared by direct dissolution method. Spherical micelles, wormlike micelles, tubular networks, and vesicles observed by TEM were found to be a function of DS of the hydrophobic dodecyl chain, and those self-assembled nanostructures can be explained in terms of interfacial energy and packing parameter. To our knowledge, this is the first report of diverse morphologies for a comb-like amphiphilic graft copolymer system. Our system suggests very attractive advantages for biomedical applications and for mass production of aggregates by direct dissolution into water without an organic solvent.
- Qiu H, Hudson ZM, Winnik MA, Manners I, Science, 347, 1329 (2015)
- Qiu HB, Gao Y, Du V, Harniman R, Winnik MA, Manners I, J. Am. Chem. Soc., 137(6), 2375 (2015)
- Truong NP, Quinn JF, Dussert MV, Sousa NBT, Whittaker MR, Davis TP, ACS Macro Lett., 4, 381 (2015)
- Allen C, Maysinger D, Eisenberg A, Colloids Surf. B: Biointerfaces, 16, 3 (1999)
- Kapishon V, Whitney RA, Champagne P, Cunningham MF, Neufeld RJ, Biomacromolecules, 16(7), 2040 (2015)
- Such GK, Yan Y, Johnston APR, Gunawan ST, Caruso F, Adv. Mater., 27(14), 2278 (2015)
- Park W, Bae BC, Na K, Biomaterials, 77, 227 (2016)
- Kanamala M, Wilson WR, Yang M, Palmer BD, Wu Z, Biomaterials, 85, 152 (2016)
- Kim HC, Kim E, Jeong SW, Lee SG, Lee SJ, Lee SW, Macromol. Res., 23(2), 196 (2015)
- Kim HM, Lee H, Macromol. Res., 23(2), 129 (2015)
- Wang Q, Liu S, Sheng W, Guang N, Li X, Macromol. Res., 23(7), 607 (2015)
- Borisov OV, Zhulina EB, Macromolecules, 38(6), 2506 (2005)
- Kang HS, Yang SR, Kim JD, Han SH, Chang IS, Langmuir, 17(24), 7501 (2001)
- Yang SR, Jeong JH, Park K, Kim JD, Colloid Polym. Sci., 281, 852 (2003)
- Jeong JH, Kang HS, Yang SR, Kim JD, Polymer, 44(3), 583 (2003)
- Williams RJ, Pitto-Barry A, Kirby N, Dove AP, O'Reilly RK, Macromolecules, 49(7), 2802 (2016)
- Reddy KR, Lee JP, Kim JY, Lee JY, J. Nanosci. Nanotechnol., 8, 5632 (2008)
- Reddy KR, Sin BC, Ryu KS, Kim JC, Chung H, Lee JY, Synth. Met., 159, 595 (2009)
- Reddy KR, Hassan M, Gomes VG, Appl. Catal. A: Gen., 489, 1 (2015)
- Jiang GB, Quan D, Liao K, Wang H, Mol. Pharm., 3, 152 (2006)
- Lee HJ, Yang SR, An EJ, Kim JD, Macromolecules, 39(15), 4938 (2006)
- Tomida M, Nakato T, Matsunami S, Kakuchi T, Polymer, 38(18), 4733 (1997)
- Yu K, Eisenberg A, Macromolecules, 31(11), 3509 (1998)
- Raez J, Manners I, Winnik MA, J. Am. Chem. Soc., 124(35), 10381 (2002)
- Sunintaboon P, Ho KM, Li P, Cheng SZD, Harris FW, J. Am. Chem. Soc., 128(7), 2168 (2006)
- Malardier-Jugroot C, van de Ven TGM, Cosgrove T, Richardson RM, Whitehead MA, Langmuir, 21(22), 10179 (2005)
- Malardier-Jugroot C, van de Ven TGM, Whitehead MA, Mol. Simul., 31, 173 (2005)
- Liu Y, Zhong K, Li Z, Wang Y, Chen T, Lee M, Jin LY, J. Polym. Sci. A: Polym. Chem., 6, 7395 (2015)
- Lu Z, Zhong K, Liu Y, Li Z, Chen T, Jin LY, Soft Matter, 12, 3860 (2016)
- Nagarajan R, Langmuir, 18(1), 31 (2002)
- Israelachvili J, Intermolecular and Surface Forces, Academic Press, San Diego, 1992.
- Kuroda K, Fujimoto K, Sunamoto J, Akiyoshi K, Langmuir, 18(10), 3780 (2002)