Novel Fe3O4@SiO2@mTiO(2)-Au (mTiO(2): mesoporous TiO2) core-shell microspheres were fabricated by the facile and efficient methods, and they were characterized by SEM, TEM, XRD, XPS, BET, VSM, and photoelectrochemical measurements. Through the test of methylene blue (MB) degradation, the relative photocatalytic activity of four samples follows the order: Fe3O4@SiO2@mTiO(2)-Au (FSTA) > Fe3O4@SiO2@mTiO(2) (FST) > Fe3O4@mTiO(2) (FT) > P25. The superior photocatalytic property of FSTA is mainly attributed to the positive effect of three components including decorative Au nanoparticles, SiO2 intermediate layer, and mesoporous TiO2 layer. Moreover, FSTA microspheres were easily recycled by using an external magnetic field while their photocatalytic efficiency had no obvious decrease after running 6 times of photocatalytic test. The well-designed microstructure makes FSTA a highly efficient, recoverable, and stable photocatalytic system, which has promising applications in environmental treatment.