Improving the carbon resistance of Ni-based catalysts for the dry reforming of methane (DRM) through the metal-perovskite interaction is an attractive strategy. Ni-based perovskite precursors with the nominal compositions of La2NiO4 and LaNiO3, as well as their Fe partially substituted counterparts (La2Ni0.5Fe0.5O4 and LaNi0.5Fe0.5O3), were prepared by a wet impregnation method. Perovskite structures in the samples without Fe partial substitution are unstable and completely reduced during the DRM test, forming catalysts composed of Ni as the active component and La2O3 as the support. The stability of the perovskite structure is significantly enhanced by the Fe partial substitution, and improved carbon resistance are observed in these catalysts, which is attributed to the smaller particle size and better dispersion of Ni resulted from the stronger metal-support interaction. The LaNixFe1-xO3 perovskite plays an important role in the structural stability of mixed perovskite catalysts in reducing atmosphere and the enhancement of metal-support interaction. Our results indicate that the LaNi0.5Fe0.5O3 precursor synthesized by wet impregnation method is feasible to obtain stable Ni-based catalysts with high carbon resistance for DRM. (C) 2016 Elsevier B.V. All rights reserved.