Chemistry Letters, Vol.45, No.10, 1180-1182, 2016
Organic Nanotube with Subnanometer Inner Diameter Self-assembled from Carboxybetaine Bipolar Amphiphile and Its Stabilization Effect toward Small Molecules
A new carboxybetaine-based wedge-shaped bipolar amphiphile is synthesized for self-assembly into an organic nanotube (ONT) at pH 3.0, showing a small inner diameter (<1 nm). The subnanometer nanospace of ONT shows confinement effect, which stabilizes encapsulated small molecules. It shows a better effect than cyclodextrin in the protection of methylene blue from the reduction by glutathione.