Using field measurement and numerical simulation techniques, this study assessed the impact of tree shading on indoor and outdoor summer thermal conditions of two similar buildings at the Federal University of Technology Akure (FUTA), Nigeria. One of the buildings was shaded by trees, while the other was unshaded. For the numerical simulation, outdoor micro-climate model, ENVI-met and Building Energy Simulation (BES) program, EnergyPlus were integrated. This modelling approach was validated using simultaneously observed air temperature and relative humidity data inside and outside both buildings during the summer period (September-November) of year 2010. Model performance statistics results indicate reasonable agreement between simulated and observed micro-climatic data at the indoor and outdoor of both buildings. The integrated models captured the evolution and magnitude of a warm-humid micro-climate of West Africa sub-region and impact of tree-shades on local thermal comfort. Furthermore, micro-scale relationship between non-radiation based thermal comfort indices (Temperature-Humidity Index, THI and Wet Bulb Globe Temperature, WBGT) and Physiological Equivalent Temperature, PET at the interior and exterior of both buildings was investigated. Result suggests preference of WBGT to THI for the assessment of local thermal condition where technical instrumentation (required for PET estimation) and/or model capability is lacking irrespective of shading condition and environment (indoor or outdoor). (C) 2016 Elsexiier B.V. All rights reserved.