Measured quaternary and ternary liquid-liquid equilibrium for 2-methoxy-2-methylbutane (tert-amyl methyl ether, TAME) with furfural, acetic acid, and water are presented in the temperature range between 298 and 341 K. In addition, binary pairs for TAME + water and furfural + water were measured in the range between 298 and 341 K. Results were modeled with UNIQUAC-HOC (Hayden-O'Connell) activity coefficient model and corresponding binary interaction parameters are presented along with measurement data. Solvent suitability for industrial use was assessed for 2-methoxy-2-methylbutane and compared to 2-methoxy-2-methylpropane and other industrial solvents.