The catalytic conversion of substituted and unsubstituted cyclohexanones to the corresponding enones and aromatic alcohol catalyzed by Pd, Pd-1, Pd-cube, Cu, Ni, Ag@Pd and Ni-Sn nanocatalysts has been studied in the presence of O-2 as the oxidant without using any additives i.e. acid or base or ligand. The optimization of experimental parameters for dehydrogenation of cyclohexanones was established to achieve maximum yield of the product by using Pd nanocatalyst. The conversion of cyclohexanone, cyclohexenone, 3-methyl cyclohexanone and 3-methyl cyclohexenone catalyzed by Pd nanocatalyst at 80 degrees C, 10 atm O-2 pressure after 24 h, led to a 79%, 49%, 62% and 25% yields of desired products, respectively. Then, the conversion of substituted and unsubstituted cyclohexanones investigated in the presence of various nanocatalysts i.e., Pd-1, Pd-cube, Cu, Ni,Ag@Pd and Ni-Sn nanoparticles and was compared their percentage yields. (C) 2016 Elsevier B.V. All rights reserved.