The renewability of bio-glycerol has made it an attractive platform for the production of diverse compounds. Selective hydrogenolysis of glycerol to propylene glycol (PG) is one of the most promising routes for glycerol valorization, since this compound is an important chemical intermediate in a number of applications. In this article, advancements in the catalytic conversion of glycerol into propylene glycol are reviewed, which include advances in process development, effects of preparation and activation methods on catalytic activity and stability, and the performance of various types of catalysts. The feasibility of using bio-hydrogen and the challenges of utilizing crude glycerol for glycerol hydrogenolysis are also discussed.